Tattoos may be appropriate for removal by excision in one stage under local anesthesia in the office by excision. Whether or not this can be done varies widely, depending upon its size and location.

The most successful areas for tattoo excision are the backs of the fingers, groin, lower abdomen, lower breast, and other areas depending on the size and laxity of the skin. In some cases, multiple excisions are required with an interval of several weeks apart in order to remove the entire tattoo.